News

BioWales 2016 – Registration now open!

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Registration is now open for BioWales, the leading UK Life Sciences conference – with a discount of 40% available for early bird registration.

The theme for 2016 is Connect and Collaborate, with the event offering a unique platform in Wales to develop new international connections and partnering opportunities.

Lord Winston is the first of the big names to be announced in our inspirational, world class speaker programme. BioWales 2016 also showcases:

  • Expert-led collaborative workshops and round table sessions, focusing on funding, research, skills and technology.
  • The latest on how the Life Sciences Hub Wales is connecting, inspiring and accelerating growth.
  • Dragon’s Den, with financial rewards for the best entrepreneur pitch.
  • 1-to-1 partnering offering high-value connections and deal making prospects.

PLUS new to 2016 – a refreshed Website, VIP Breakfast Briefing, Micro SME Rate; and Innovation Zone allowing entrepreneurial SMEs to showcase their products and get ‘access-to-expert’ advice.

To register as a delegate please visit BioWales 2016

There are also great opportunities for Exhibitors and Sponsors.

Be part of it!

Follow us on @BioWales using #biowales2016


Cancer Free Future Event a Great Success

Tenovus Cancer Care joined forces with the Life Sciences Research Network Wales to showcase the very latest advances in the fight against cancer.

Experts from across the UK met at the Life Sciences Hub at Cardiff Bay to discuss the very latest advancements in cancer research to an audience which included PhD students funded by Tenovus Cancer Care, key supporters of the charity and Deputy Health Minister Vaughan Gething AM.

CPAlCnLWIAA99_aAmong the speakers were Hugh Griffiths, whose work with Professor Chris McGuigan has led to the development of Acelarin, which is helping to control the spread of solid tumours in cancer patients.

Professor McGuigan, Chair of Life Sciences Research Network Wales and the Life Sciences Hub Wales, and inventor of Acelarin, said: “At the National Research Network, we are proud to work with Tenovus in bringing better drugs forward to improve the treatment of cancer in patients across Wales, and beyond,”

Each year Tenovus Cancer Care invests nearly £0.5 million across 20 PhD projects making us one of the largest supporters of early career researchers and scientists in Wales. We are also pleased to announce that starting this October we will be investing a further £900,000 in 10 PhD studentships based at Cardiff, Swansea and Bangor Universities.

This year Tenovus Cancer Care has partnered with the Life Sciences Research Network (LSRN) to jointly support a PhD studentship in cancer drug development.

These studentships span a breadth of cancer research areas, including drug development, immunotherapy, cancer genetics and prostate cancer treatment choices.

Dr Ian Lewis, Director of Research at Tenovus Cancer Care, said: “Wales is at the forefront of some really exciting developments in cancer research. We are really proud to be working with the Life Sciences Research Network to support this PhD studentship, which will help us develop new drugs to combat cancer.”

Deputy Health Minister Vaughan Gething AM added: “We have made real progress in improving cancer care in Wales – more people than ever now survive cancer, even though more people are being diagnosed.”

“The work of Tenovus is a fantastic example of how the third sector and NHS Wales work together to meet the needs of patients. My hope is such ongoing collaboration can continue to support society’s wider efforts to tackle the burden of cancer on individuals and the health service.”


Antimicrobial Resistance Call

Antimicrobial Resistance (AMR) in the Real World is a £6.5m programme under the AMR Cross-Research Council initiative which is funded by NERC, BBSRC and MRC.  This programme has recently launched a call for Pump Priming Grants of up to £200k to address the need for a greater understanding of the role of the outdoor environment and host microbiome in influencing the evaluation, acquisition and spread of antibacterial resistance.  The research can be based in agricultural, aquaculture, wastewater and natural environments (and their interfaces), the human and animal host microbiome, and also includes elements of the way people and human communities interact with the environment.
Whilst not directly relevant to drug development, the call may be of interest to some of the Network’s members.
 
Please note that there is town hall meeting on the 11th of September in London where applicants can discuss their proposals with the funders and potential collaborators.
 
Further information can be found at the following website: http://www.nerc.ac.uk/research/funded/programmes/amr/news/ao-ppgrants/

Cardiff Cancer Research Open Day

Cardiff University’s European Cancer Stemcell Research Institute, Velindre NHS Trust and Cancer Research UK  will be holding a Cancer Research Open Day on Saturday 24th October at the Hadyn Ellis Building, Maindy Road (posters attached).

This public event will showcase the diverse, cutting-edge cancer research taking place across Cardiff and attendees from across Wales are welcome. The event is aimed primarily at members of the public but visitors will meet cancer scientists, doctors and nurses, go behind the scenes on lab tours, learn about local research through talks and interactive demos and create some biological artwork with local textile artist, Lisa Porch.

Attendance is free and visitors can register their interest at https://www.eventbrite.co.uk/e/cardiff-cancer-research-open-day-2015-tickets-18114580197.

For further information please see the attached posters.

Cancer research open day 2015 poster Welsh

Cancer research open day 2015 poster English


Longitude Prize

£10m to conserve antibiotics for future generations

Thursday 24th September

18:00-20:00, Life Sciences Hub, 3 Assembly Square, Cardiff. Wales. CF10 4PL

Refreshments will be provided

Nesta and Life Sciences Hub Wales would like to invite you to come and find out more about the £10m Longitude Prize’s fascinating 300-year history, last year’s BBC Horizon vote and what you need to do to win the Prize.
The Longitude Prize is a historic challenge that aims to conserve antibiotics for future generation. The challenge is to develop a cheap, accurate, rapid and easy-to-use, point-of-care test that will identify when antibiotics are needed and, if they are, which ones to use.

The Longitude Prize was opened last year and will run until December 2019 or until a winner is found.

Find out more about how to win the Longitude Prize – sign up now

The event will be hosted by Adam Price

You will hear from:

Dr Tracey Cooper

Chief Executive – Public Health Wales

Professor Chris Butler

Professor of Primary Care Medicine and Longitude Prize Judging Panel member

Professor Jim McLaughlin OBE

Professor in the University of Ulster School of Engineering & Chief Technology Officer – Zensor

Reserve your place now

 

 

 


Crowdfunding for Research in Life Sciences

Cardiff University are looking to support a number of research projects through innovative crowdfunding company FutSci. Crowdfunding, in its simplest form, is a way of raising funds by asking a large number of people to contribute a relatively small amount of money. Futsci specialises in funding biomedical research through crowdfunding and provide the opportunity for individual to support specific research projects.

For more information, please visit their website, https://www.futsci.com


MEP-Scientist Pairing Scheme 2015

The European Parliament is issuing an invitation for academics to take part in the ‘MEP-Scientist Pairing Scheme 2015’.  The EU recognise the importance of scientific expertise in informing policy-maker dealing with global challenges, from climate change to feeding the world, from an ageing population to energy security.  The MEP-Scientist Pairing Scheme provides an opportunity for scientists to influence policy makers and gain a better understanding of the EU science, technology and research policy framework.
Interested parties should download the application form for more details (website).  Please note that the deadline for application is the 31st of July 2015.

AMR

Anti Microbial Resistance

Antimicrobial resistance is a growing public health issue that threatens to undermine the treatment of an increasing range of infections caused by bacteria, viruses and fungi. Many of the most commonly used antimicrobials are becoming less effective with bacteria, viruses and fungi naturally adapting and becoming increasingly resistant to medicines used to treat the infections they cause.

This is a global problem that the Work Economic Forum and World Health Organisation have both identified as a major public health problem.

The issue has also been raised by the UK’s Chief Medical Officer and resulted in the Department of Health releasing a Five Year Antimicrobial Resistance Strategy (2013-18).

Academics from across Wales have a long track record of research into antimicrobial resistance and are working together to address key challenges in the following areas:

Alternative Approaches to Treating Bacterial Infection
Development of Novel Therapeutics
Development of Diagnostic Devices.
The consortium includes members from the following Welsh universities:

Aberystwyth, Bangor, Cardiff and Swansea.

If you are interested in joining the forum or finding out more, please email us nrn@cardiff.ac.uk


Recently funded Research Projects and Studentships

The Network has recently awarded the following Round 3 Research Projects and Studentships:

Research Projects:

Dr Gwenin, A rapid point of care system to manage/monitor drug treatment in therapeutically relevant mycobacterial infections

Prof O’Donnell, Development of new prothrombotic lipids for haemostatic applications

Prof Hall, Investigating the potential of the sphingosine-1-phosphate receptor 1 modulators for the treatment of psychiatric disorders.

Prof Piguet, Anti-viral activity of ProTide derivatives on human T cells

Dr Rozanowska, Novel modulators of the visual cycle for treatment of retinal degenerations

Dr Kidd, Investigating a novel therapy for Alzheimer’s disease in a mouse model of amyloid pathology

Dr Clarkson, Sensitizing to radiotherapy: ore-clinical evaluation of a novel indication for adjuvant bcl3i

Prof Dale, Establishing a screen for the WNT-STOP mitotic signalling pathway

Prof Wilkinson, Expression and activity determination of novel cloned antibiofilm peptides

Dr Westwell, Advancing analogues of a novel cFLIP inhibitor which sensitises breast cancer cells and cancer stem cells to TRAIL

Studentships:

Dr Heard, Towards the repurposing existing of topical antimicrobials by ligand complexation.

Prof Hoffmann, Repositioning histone methyltransferase inhibitors as next generation anthelmintics.

Prof Mur, Exploiting natural products from Hops (Humulus lupulus) to suppress tuberculosis.

Prof Sheldon, Manipulation of squalene synthase to limit bacterial infections.

Dr Howell, Treating Progressive Multiple Sclerosis Using A Novel Neuroprotective And Anti-Inflammatory approach.

Dr Del Sol, Companion diagnostic development guides Antibody-Drug Conjugate formulation: Implications for patient stratification and precision medicine.

Dr Cai, Combining carbon monoxide (CO)-releasing molecules with anti-VEGF therapy for triple-negative breast cancer therapy.

Prof Doak, Design and evaluation of an antibody-drug conjugate for prostate cancer treatment.

Prof Brophy, Towards validation of an immune suppressor protein from liver fluke as a drug target.

Prof Triantafilou, Peptides derived from Yersinia pestis V antigen as novel therapeutic interventions for sepsis.

Prof Doak, Mechanistic evaluation of the impact of superparamagnetic iron oxide nanoparticles conjugated with drugs (SPIONd) on intracellular signalling/homeostatic mechanisms.

Dr Creevey, Computational approaches to mining the rumen micro biome for novel antimicrobials.

Dr Gwenin, Testing a novel chemotherapy delivery system using two dinitrobenzamide mustard prodrugs.


European Institute of Innovation Technology (EIT) partnership workshop on diet, metabotypes and healthy living

The Life Science Research Network is supporting an European Institute of Innovation Technology (EIT)  partnership workshop on diet, metabotypes and healthy living next Tuesday the 19th of May in the Life Science Hub at Cardiff Bay.   This event is being led by Aberystwyth University and will be of most value to individuals and businesses interested in bringing new health innovations in precision nutrition and diagnostics to market. The event is open to all but places are limited. For further information, please contact Lia Tseki at evt3@aber.ac.uk.
EIT Health (http://eit.europa.eu/eit-community/eit-health) is the newly designated Knowledge and Innovation Community (KIC) for Healthy Living and Active Ageing. KICs are a unique type of partnership within the European innovation landscape and develop innovative products and services, foster new business, encourage growth, and train a new generation of entrepreneurs. Characterised by a high degree of integration, a long-term perspective, efficient governance, the co-location model and an entrepreneurial culture, KICs aim to increase Europe’s capacity for innovation by bringing together leading companies, universities, and research labs.